Isotroin 5 Capsule contains isotretinoin 5 mg, a retinoid derivative primarily indicated for the treatment of severe recalcitrant nodular acne that is unresponsive to conventional therapies such as antibiotics and topical agents. Isotretinoin acts by reducing sebaceous gland size and sebum production, inhibiting the growth of acne-causing bacteria, and exerting anti-inflammatory effects, thereby addressing multiple pathogenic factors of acne vulgaris. The capsule formulation allows for precise dosing and improved patient compliance. Isotroin 5 is typically prescribed under strict medical supervision due to its potent pharmacological activity and potential adverse effects. Common side effects include dry skin, cheilitis, and photosensitivity, while more serious risks involve teratogenicity, hepatotoxicity, and lipid abnormalities, necessitating regular monitoring of liver function tests and lipid profiles during treatment. Patients of childbearing potential must adhere to stringent pregnancy prevention programs due to the high risk of fetal malformations. Dose adjustments may be required based on therapeutic response and tolerability. Isotroin 5 Capsule should be used as part of a comprehensive acne management plan, including skin care guidance and avoidance of aggravating factors. It is contraindicated in pregnancy, hypersensitivity to isotretinoin, and certain metabolic disorders.