Isac 10 Capsule contains isotretinoin 10 mg, a retinoid derivative primarily indicated for the treatment of severe recalcitrant nodular acne that is unresponsive to conventional therapies including antibiotics. Isotretinoin acts by reducing sebaceous gland size and sebum production, inhibiting the growth of Propionibacterium acnes, and exerting anti-inflammatory effects, thereby addressing multiple pathogenic factors involved in acne development. This medication is typically prescribed under strict medical supervision due to its potent efficacy and potential for serious adverse effects. Patients should undergo baseline and periodic liver function tests, lipid profiles, and pregnancy testing prior to and during therapy, as isotretinoin is highly teratogenic and contraindicated in pregnancy. Common side effects include dry skin, cheilitis, conjunctivitis, and transient elevations in liver enzymes and lipid levels. Dose adjustments may be necessary based on tolerance and laboratory findings. Isac 10 Capsule should be taken with food to enhance absorption. Patients are advised to avoid excessive sun exposure and use appropriate skin moisturizers. Due to its risk profile, isotretinoin therapy requires careful patient education regarding adherence, monitoring, and contraception to ensure safe and effective treatment outcomes.