Heptilose Oral Solution contains Lactulose 10gm per dose and is indicated primarily for the treatment of chronic constipation and hepatic encephalopathy. Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but undergoes fermentation by colonic bacteria, resulting in the production of organic acids that lower colonic pH and promote osmotic retention of water. This mechanism facilitates softening of stools and increases bowel movement frequency, making it effective for relieving constipation. Additionally, in patients with hepatic encephalopathy, lactulose reduces blood ammonia levels by acidifying the colon, converting ammonia (NH3) to ammonium (NH4+), which is less absorbable, thereby reducing systemic toxicity. Heptilose Oral Solution is administered orally, with dosage individualized based on clinical response and patient tolerance. Common side effects may include flatulence, abdominal discomfort, and diarrhea, which are generally mild and transient. It is contraindicated in patients with galactosemia and intestinal obstruction. Caution is advised in diabetic patients due to the sugar content. Regular monitoring of electrolyte balance and hydration status is recommended during prolonged use. Heptilose Oral Solution offers a well-established, effective therapeutic option for managing constipation and hepatic encephalopathy in clinical practice.