Gramocef-OF Tablet

Gramocef-OF Tablet
Cefixime (200mg) + Ofloxacin (200mg)
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About This Medicine
Product description & overview
Gramocef-OF Tablet is a combination antibiotic formulation containing Cefixime 200 mg and Ofloxacin 200 mg, designed for the treatment of a broad spectrum of bacterial infections. Cefixime, a third-generation cephalosporin, acts by inhibiting bacterial cell wall synthesis, leading to cell lysis and death, while Ofloxacin, a fluoroquinolone, exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. This synergistic combination enhances efficacy against both Gram-positive and Gram-negative pathogens, including strains resistant to monotherapy. Gramocef-OF is indicated for respiratory tract infections, urinary tract infections, gastrointestinal infections, skin and soft tissue infections, and sexually transmitted infections caused by susceptible organisms. The tablet should be administered as prescribed by a healthcare professional, typically once or twice daily, with or without food. Caution is advised in patients with a history of hypersensitivity to cephalosporins or fluoroquinolones, and it is contraindicated in individuals with known tendon disorders related to fluoroquinolone use. Potential side effects include gastrointestinal disturbances, hypersensitivity reactions, and, rarely, tendonitis or tendon rupture. Proper adherence to the prescribed dosage and duration is essential to prevent antibiotic resistance and ensure therapeutic success.
Active composition
Ofloxacin 200 mg
+1 more active ingredient
About Ofloxacin
Ofloxacin is a fluoroquinolone antibiotic used to treat various bacterial infections. It works by inhibiting DNA gyrase, preventing bacterial replication. This medication is essential for managing bacterial infections. In summary, Ofloxacin is effective in treating a wide range of bacterial infections.
How It Works
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
All Active Ingredients
Cefixime
Cefixime disrupts the synthesis of the bacterial cell wall, leading to bacterial lysis and death.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Gramocef-OF Tablet.
High Risk
Pregnancy
Gramocef-OF Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Gramocef-OF Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Liver
Gramocef-OF Tablet should be used with caution in patients with liver disease. Dose adjustment of Gramocef-OF Tablet may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Gramocef-OF Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Gramocef-OF Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gramocef-OF Tablet may be needed. Please consult your doctor.
Regular Checkup
Customer Reviews
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