Gramocef-O 200mg Tablet DT contains Cefixime 200mg, a third-generation cephalosporin antibiotic effective against a broad spectrum of gram-positive and gram-negative bacterial infections. Cefixime acts by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. This formulation is designed as a dispersible tablet, allowing rapid dissolution in water for ease of administration, particularly beneficial for patients with swallowing difficulties. Gramocef-O 200mg is indicated for the treatment of various bacterial infections including uncomplicated urinary tract infections, acute otitis media, pharyngitis, tonsillitis, bronchitis, and certain cases of gonorrhea. It is effective against pathogens such as Escherichia coli, Haemophilus influenzae, Proteus mirabilis, and Streptococcus species. The drug should be used according to susceptibility testing and prescribed dosage to minimize resistance development. Common adverse effects may include gastrointestinal disturbances such as diarrhea, nausea, and abdominal discomfort. Hypersensitivity reactions, though rare, require immediate medical attention. Caution is advised in patients with a history of penicillin or cephalosporin allergy. Gramocef-O 200mg should be administered under medical supervision, with dosage adjustments in renal impairment. Proper adherence to the prescribed regimen is essential to ensure therapeutic efficacy and prevent recurrence.