Zuka-Minic Syrup is a combination pharmaceutical formulation containing Chlorpheniramine Maleate (2mg/5ml) and Phenylephrine (5mg/5ml), designed for the symptomatic relief of allergic conditions and nasal congestion. Chlorpheniramine Maleate is a first-generation antihistamine that competitively inhibits H1 histamine receptors, thereby alleviating symptoms such as sneezing, runny nose, itching, and watery eyes associated with allergic rhinitis and other hypersensitivity reactions. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that acts as a decongestant by inducing vasoconstriction in the nasal mucosa, reducing swelling and nasal congestion. Zuka-Minic Syrup is indicated for use in conditions such as common cold, allergic rhinitis, sinusitis, and other upper respiratory tract allergies where both antihistaminic and decongestant effects are desired. The syrup formulation facilitates ease of administration, particularly in pediatric and geriatric populations. Dosage should be determined based on age, weight, and severity of symptoms, and it is essential to adhere to recommended guidelines to minimize adverse effects such as drowsiness, dry mouth, increased blood pressure, or palpitations. Contraindications include hypertension, hyperthyroidism, and sensitivity to any component. Consultation with a healthcare professional is advised before use, especially in patients with underlying medical conditions or those taking other medications.