Zosa Tablet contains Esomeprazole 40 mg, a proton pump inhibitor indicated for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, and other conditions involving excessive stomach acid production. Esomeprazole acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing basal and stimulated gastric acid secretion. This reduction in gastric acidity promotes healing of acid-related mucosal damage and alleviates symptoms such as heartburn, acid regurgitation, and epigastric discomfort. Zosa Tablet is typically administered orally once daily, preferably before meals, and the dosage may be adjusted based on clinical response and the severity of the condition. It is generally well tolerated; however, potential adverse effects include headache, diarrhea, nausea, abdominal pain, and dizziness. Long-term use should be monitored due to possible risks such as vitamin B12 deficiency, hypomagnesemia, and increased susceptibility to gastrointestinal infections. Zosa Tablet should be used cautiously in patients with hepatic impairment and is contraindicated in individuals with known hypersensitivity to esomeprazole or other proton pump inhibitors. Consultation with a healthcare professional is recommended before initiating therapy to ensure appropriate use and to monitor therapeutic outcomes.