Xorel 20 Tablet contains Rabeprazole 20 mg, a proton pump inhibitor (PPI) used primarily to reduce gastric acid secretion. It is indicated for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, and peptic ulcer disease. Rabeprazole acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing the final step in acid production. This mechanism results in a significant and prolonged reduction of gastric acid secretion, promoting healing of acid-related mucosal damage and alleviating symptoms such as heartburn and acid regurgitation. Xorel 20 is typically administered orally once daily, preferably before meals, with dosage adjustments based on clinical response and specific indications. It is generally well tolerated; however, potential adverse effects may include headache, diarrhea, nausea, abdominal pain, and dizziness. Long-term use should be monitored due to risks of vitamin B12 deficiency, hypomagnesemia, and increased susceptibility to gastrointestinal infections. Xorel 20 should be used cautiously in patients with hepatic impairment and is contraindicated in individuals with known hypersensitivity to Rabeprazole or other PPIs. Consultation with a healthcare professional is recommended before initiating therapy to ensure appropriate use and monitoring.