Zonimid 100 Capsule contains Zonisamide 100 mg, an anticonvulsant medication primarily indicated for the management of partial seizures in patients with epilepsy. Zonisamide exerts its therapeutic effect by stabilizing neuronal membranes and suppressing abnormal electrical activity in the brain through modulation of voltage-gated sodium and calcium channels. This action reduces the frequency and severity of seizure episodes. Zonimid 100 is typically prescribed as adjunctive therapy in adults and pediatric patients over the age of 16 years who have refractory partial seizures. The capsule formulation allows for convenient oral administration, with dosing individualized based on clinical response and tolerability. Common adverse effects may include dizziness, somnolence, headache, and gastrointestinal disturbances, while serious side effects such as hypersensitivity reactions or metabolic acidosis are rare but warrant immediate medical attention. Caution is advised in patients with sulfonamide allergy, renal impairment, or a history of kidney stones. Regular monitoring of renal function and serum bicarbonate levels is recommended during prolonged therapy. Zonimid 100 should be used under strict medical supervision, with gradual dose titration to minimize adverse effects and optimize seizure control. It is important to adhere to prescribed dosing schedules and not discontinue therapy abruptly to prevent seizure exacerbation.