Zitrazole-IT Anti Fungal Cream

Zitrazole-IT Anti Fungal Cream
Ofloxacin (0.75% w/w) + Ornidazole (2% w/w) + Itraconazole (1% w/w) + Clobetasol (0.05% w/w)
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About This Medicine
Product description & overview
Zitrazole-IT Anti Fungal Cream is a potent topical formulation combining Ofloxacin (0.75% w/w), Ornidazole (2% w/w), Itraconazole (1% w/w), and Clobetasol (0.05% w/w) designed for the effective management of mixed fungal and bacterial skin infections accompanied by inflammation and pruritus. Ofloxacin, a broad-spectrum fluoroquinolone antibiotic, targets bacterial pathogens by inhibiting DNA gyrase, thereby preventing bacterial replication. Ornidazole, a nitroimidazole derivative, exhibits activity against anaerobic bacteria and protozoa, enhancing the antimicrobial spectrum. Itraconazole, a triazole antifungal agent, impedes fungal cell membrane synthesis by inhibiting ergosterol production, effectively treating dermatophytic and yeast infections. Clobetasol propionate, a potent corticosteroid, provides anti-inflammatory, antipruritic, and vasoconstrictive effects, reducing erythema, swelling, and discomfort associated with inflammatory dermatoses. This combination cream is indicated for dermatophytosis, candidiasis, mixed bacterial-fungal infections, and inflammatory dermatoses where secondary infection is present. Application should be limited to affected areas, avoiding prolonged use to minimize potential corticosteroid-related adverse effects such as skin atrophy. Contraindications include hypersensitivity to any component and viral or tubercular skin infections. Zitrazole-IT offers a comprehensive therapeutic approach, addressing infection and inflammation simultaneously to promote rapid symptom resolution and skin healing.
Active composition
Ofloxacin
+3 more active ingredients
About Ofloxacin
Ofloxacin is a fluoroquinolone antibiotic used to treat various bacterial infections. It works by inhibiting DNA gyrase, preventing bacterial replication. This medication is essential for managing bacterial infections. In summary, Ofloxacin is effective in treating a wide range of bacterial infections.
How It Works
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
All Active Ingredients
Ornidazole
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Itraconazole
Itraconazole inhibits the synthesis of ergosterol, disrupting fungal cell membrane integrity.
Clobetasol
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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