ZO Eye/Ear Drops contain Ofloxacin 0.3% w/v, a broad-spectrum fluoroquinolone antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria. This formulation is indicated for the treatment of bacterial infections of the eye and ear, including conjunctivitis, keratitis, blepharitis, otitis externa, and otitis media caused by susceptible organisms. Ofloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, thereby exerting a bactericidal effect. ZO Eye/Ear Drops are suitable for topical administration, ensuring targeted delivery to the affected site with minimal systemic absorption. The product is typically administered as one to two drops in the affected eye or ear every four to six hours, with the duration of therapy depending on the severity and type of infection, usually ranging from 7 to 10 days. Patients should be advised to complete the full course of treatment to prevent the development of resistance. Precautions include avoiding contact with contact lenses during treatment and monitoring for potential hypersensitivity reactions. ZO Eye/Ear Drops should be stored at room temperature, protected from light and moisture. This medication is contraindicated in patients with known hypersensitivity to ofloxacin or other quinolones.