Zeoflox OZ 200mg/500mg Tablet is a combination antibiotic formulation containing Ofloxacin 200mg and Ornidazole 500mg, indicated for the treatment of various bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing DNA replication and transcription. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by causing DNA strand breakage and inhibiting nucleic acid synthesis. This synergistic combination is particularly useful in managing mixed infections involving aerobic and anaerobic organisms, such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, and skin and soft tissue infections. Zeoflox OZ is also employed in the treatment of amoebiasis and giardiasis. The tablet should be administered as prescribed by a healthcare professional, with dosage adjustments based on the severity of infection and patient-specific factors such as renal function. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles, and it is contraindicated during pregnancy and lactation unless clearly necessary. Common adverse effects include gastrointestinal disturbances, headache, and dizziness. Proper adherence to the prescribed regimen is essential to prevent resistance development.