Zenicool 120 Capsule contains Orlistat 120 mg, a potent lipase inhibitor indicated for the management of obesity. It acts by selectively inhibiting gastric and pancreatic lipases, enzymes responsible for the hydrolysis of dietary triglycerides into absorbable free fatty acids and monoglycerides. By preventing the breakdown and subsequent absorption of approximately 30% of dietary fat, Zenicool 120 facilitates weight reduction and assists in weight maintenance when used alongside a reduced-calorie, low-fat diet. This medication is prescribed for adults with a body mass index (BMI) of 30 kg/m² or greater, or those with a BMI of 27 kg/m² or greater who have additional risk factors such as hypertension, type 2 diabetes mellitus, or dyslipidemia. The recommended dosage is one 120 mg capsule taken orally three times daily with each main meal containing fat. Adherence to dietary fat intake recommendations is crucial to minimize gastrointestinal adverse effects, which may include oily spotting, flatulence with discharge, fecal urgency, and increased defecation. Zenicool 120 is contraindicated in patients with chronic malabsorption syndrome or cholestasis. Regular monitoring of liver function and fat-soluble vitamin levels is advised during prolonged therapy. This medication should be used under medical supervision to ensure safe and effective weight management.