Onslim Capsule contains Orlistat 120mg, a potent lipase inhibitor indicated for the management of obesity in conjunction with a reduced-calorie diet and increased physical activity. Orlistat acts locally within the gastrointestinal tract by selectively inhibiting pancreatic and gastric lipases, enzymes responsible for the hydrolysis of dietary triglycerides into absorbable free fatty acids and monoglycerides. By preventing the breakdown and subsequent absorption of approximately 30% of ingested fat, Onslim Capsule facilitates weight reduction and helps improve weight-related comorbidities such as hypertension, dyslipidemia, and type 2 diabetes mellitus. The recommended dosage is one 120mg capsule taken orally three times daily with each main meal containing fat. To optimize efficacy and minimize gastrointestinal adverse effects, patients should adhere to a nutritionally balanced, reduced-calorie diet with controlled fat intake. Common side effects include oily spotting, flatulence with discharge, fecal urgency, and increased defecation, which typically diminish over time with dietary adjustments. Onslim Capsule is contraindicated in patients with chronic malabsorption syndrome, cholestasis, or hypersensitivity to Orlistat. Caution is advised when co-administered with fat-soluble vitamins; supplementation may be necessary. Regular monitoring and lifestyle modifications are essential to achieve sustained weight management outcomes.