Zedex AF Syrup is a combination medication containing Chlorpheniramine Maleate (2mg) and Phenylephrine (5mg) per dose, formulated to provide effective relief from symptoms associated with allergic conditions and nasal congestion. Chlorpheniramine Maleate is an antihistamine that works by blocking H1 histamine receptors, thereby reducing allergic manifestations such as sneezing, runny nose, itching, and watery eyes. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that acts as a nasal decongestant by constricting blood vessels in the nasal mucosa, leading to decreased swelling and improved airflow. Zedex AF Syrup is indicated for the symptomatic treatment of allergic rhinitis, common cold, sinusitis, and other upper respiratory tract conditions characterized by nasal congestion and allergic symptoms. The combination offers a dual mechanism of action, addressing both histamine-mediated allergic reactions and nasal congestion effectively. It is recommended to use this medication as directed by a healthcare professional, taking into consideration patient-specific factors such as age, medical history, and concomitant medications. Caution is advised in patients with hypertension, cardiovascular disease, glaucoma, or hyperthyroidism. Adverse effects may include drowsiness, dry mouth, dizziness, and increased blood pressure. Consult a healthcare provider if symptoms persist or worsen.