Xtragyl-M Oral Suspension Mango is a combination antibiotic and antiflatulent formulation containing Ofloxacin 50mg, Metronidazole 120mg, and Simethicone 10mg per 5ml. Ofloxacin, a fluoroquinolone antibiotic, exhibits broad-spectrum bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, effective against various gram-positive and gram-negative pathogens. Metronidazole, a nitroimidazole derivative, provides potent activity against anaerobic bacteria and protozoa by disrupting DNA synthesis. Simethicone acts as an anti-foaming agent, reducing bloating and discomfort caused by excess gas in the gastrointestinal tract. This oral suspension is indicated for the treatment of mixed infections involving susceptible aerobic and anaerobic bacteria, including gastrointestinal infections such as bacterial diarrhea, amoebiasis, and infections complicated by gas-related symptoms. The mango-flavored formulation enhances palatability, improving patient compliance, especially in pediatric and adult populations requiring oral therapy. Xtragyl-M should be used under medical supervision with dosage adjusted according to infection severity and patient condition. Caution is advised in patients with hypersensitivity to any component, and it is contraindicated in pregnancy and lactation unless benefits outweigh risks. Adverse effects may include gastrointestinal disturbances, hypersensitivity reactions, and potential interactions with other medications. Proper adherence to prescribed dosage and duration is essential to prevent resistance development.