Medibook DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Pantoprazole 40mg, designed for the management of upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and gastric discomfort. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these two agents addresses both the symptomatic and pathophysiological aspects of acid-related gastrointestinal disorders, enhancing therapeutic efficacy. Medibook DSR Capsule is indicated for patients presenting with dyspeptic symptoms, delayed gastric emptying, and acid reflux, particularly when monotherapy is insufficient. It is generally well-tolerated; however, it should be used with caution in patients with known hypersensitivity to either component, cardiac arrhythmias, or hepatic impairment. The dosage and duration of therapy should be individualized based on clinical response and physician assessment. Regular monitoring is recommended to detect potential adverse effects, ensuring safe and effective treatment outcomes.