Wonmet G2 Forte Tablet SR is a combination oral hypoglycemic agent containing Glimepiride 2mg and Metformin 1000mg, formulated for sustained release to provide effective glycemic control in patients with type 2 diabetes mellitus. Glimepiride, a sulfonylurea class drug, stimulates pancreatic beta cells to enhance insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production, improving peripheral insulin sensitivity, and enhancing glucose uptake in muscle tissues. The sustained-release formulation ensures a gradual release of the active ingredients, minimizing gastrointestinal side effects commonly associated with metformin and promoting better patient compliance through once-daily dosing. Wonmet G2 Forte is indicated as an adjunct to diet and exercise to improve glycemic control in adults inadequately controlled on monotherapy or diet alone. It is essential to monitor blood glucose levels regularly and adjust the dosage based on therapeutic response and tolerability. Caution is advised in patients with renal or hepatic impairment, and contraindications include severe renal dysfunction, metabolic acidosis, and hypersensitivity to components. This combination therapy offers a synergistic approach to managing hyperglycemia by targeting multiple pathophysiological defects in type 2 diabetes.