Oriel Tablet contains Levocetirizine 5mg, a third-generation non-sedating antihistamine primarily used for the relief of allergic symptoms. Levocetirizine is the active enantiomer of cetirizine and acts as a selective antagonist of peripheral H1 histamine receptors, thereby inhibiting the effects of histamine, a key mediator in allergic reactions. Oriel Tablet is indicated for the treatment of allergic rhinitis, including seasonal and perennial forms, as well as chronic idiopathic urticaria characterized by symptoms such as sneezing, nasal congestion, runny nose, itching, and hives. The medication is well-absorbed orally, with a rapid onset of action, providing symptomatic relief typically within one hour of administration. Oriel Tablet is generally well-tolerated, with a low incidence of sedation compared to first-generation antihistamines, making it suitable for daytime use. Common adverse effects may include headache, dry mouth, and fatigue, though these are usually mild and transient. Dose adjustment may be necessary in patients with renal impairment. Oriel Tablet should be used under medical supervision, especially in special populations such as pregnant or breastfeeding women. It is contraindicated in patients with known hypersensitivity to levocetirizine or any of its excipients.