Olez-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the effective management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and gastric discomfort. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing relief from acid-related conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis. The synergistic action of these two agents in Olez-DSR Capsule offers both symptomatic relief and promotes mucosal healing. This combination is particularly beneficial in patients experiencing delayed gastric emptying accompanied by acid-related irritation. Olez-DSR Capsule should be administered as prescribed by a healthcare professional, typically before meals to optimize therapeutic outcomes. Caution is advised in patients with known hypersensitivity to either component, and it is contraindicated in individuals with prolactinoma or gastrointestinal hemorrhage. Common adverse effects may include headache, dry mouth, or abdominal cramps. Regular monitoring and adherence to prescribed dosage are essential to maximize efficacy and minimize potential side effects.