Nozuka AF Syrup is a combination medication containing Chlorpheniramine Maleate (2mg/5ml) and Phenylephrine (5mg/5ml), formulated for the symptomatic relief of allergic conditions and nasal congestion. Chlorpheniramine Maleate is a first-generation antihistamine that competitively inhibits histamine H1 receptors, thereby alleviating symptoms such as sneezing, itching, rhinorrhea, and watery eyes associated with allergic rhinitis and other hypersensitivity reactions. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that produces vasoconstriction of the nasal mucosa, leading to decreased swelling and congestion. Nozuka AF Syrup is indicated for the management of allergic rhinitis, common cold symptoms, sinusitis, and other upper respiratory tract allergies where nasal congestion and histamine-mediated symptoms coexist. The syrup formulation allows for ease of administration, particularly in pediatric and adult patients who require symptomatic relief. Caution is advised in patients with hypertension, cardiovascular diseases, hyperthyroidism, or those taking monoamine oxidase inhibitors. Adverse effects may include drowsiness, dry mouth, dizziness, and increased blood pressure. It is recommended to use Nozuka AF Syrup under medical supervision, adhering to prescribed dosages to minimize potential side effects and interactions.