Miokool-DSR Capsule is a prescription medication containing the combination of Domperidone (30mg) and Esomeprazole (40mg) for the treatment of symptoms associated with Gastroesophageal Reflux Disease (GERD) and functional dyspepsia. This fixed-dose combination capsule is designed to provide rapid and sustained relief from heartburn, regurgitation, and upper abdominal pain. Domperidone, a dopamine D2 receptor antagonist, increases the lower esophageal sphincter tone and enhances gastric emptying, thereby reducing the frequency and severity of acid reflux episodes. Esomeprazole, a proton pump inhibitor, selectively and irreversibly inhibits the final common pathway of gastric acid secretion, thereby reducing the amount of acid produced in the stomach. The combination of these two agents provides a synergistic effect in controlling symptoms of GERD and functional dyspepsia, offering patients a convenient and effective treatment option for managing their symptoms and improving their quality of life.