Mazetol SR 200 Tablet contains Carbamazepine 200mg, an anticonvulsant and mood-stabilizing agent primarily indicated for the treatment of epilepsy, trigeminal neuralgia, and bipolar disorder. Carbamazepine acts by stabilizing the inactivated state of voltage-gated sodium channels, thereby reducing neuronal excitability and preventing the propagation of abnormal electrical discharges in the brain. Mazetol SR 200 is a sustained-release formulation designed to maintain consistent plasma drug levels, enhancing therapeutic efficacy and minimizing side effects associated with peak concentrations. It is prescribed for partial seizures with complex symptomatology, generalized tonic-clonic seizures, and mixed seizure types. Additionally, it is effective in managing neuropathic pain and acute manic episodes in bipolar disorder. Dosage should be individualized based on clinical response and tolerability, with gradual titration to minimize adverse effects such as dizziness, drowsiness, nausea, and hyponatremia. Regular monitoring of blood counts, liver function tests, and serum carbamazepine levels is recommended to detect potential hematological or hepatic toxicity. Mazetol SR 200 should be used cautiously in patients with a history of bone marrow depression, cardiac conduction abnormalities, or hypersensitivity to tricyclic compounds. Concomitant use with other CNS depressants requires careful supervision to avoid additive sedation.