Lupi-HCG 5000 Injection contains Human Chorionic Gonadotropin (hCG) at a concentration of 5000 IU per vial. It is indicated for use in both male and female patients to stimulate ovulation and support luteal phase function in assisted reproductive technologies. In males, Lupi-HCG 5000 is employed to induce spermatogenesis and treat hypogonadism by mimicking luteinizing hormone (LH) activity, thereby stimulating testosterone production by the Leydig cells in the testes. The injection is typically administered intramuscularly or subcutaneously under medical supervision, with dosage and duration tailored to the specific clinical condition and patient response. Lupi-HCG 5000 plays a critical role in infertility management protocols, including ovulation induction in anovulatory women and as part of combination therapy for male infertility. It is also used in prepubertal cryptorchidism and delayed puberty in males. Common side effects may include local injection site reactions, headache, irritability, and fatigue. Careful monitoring is essential to avoid ovarian hyperstimulation syndrome in female patients. Contraindications include hormone-sensitive tumors and hypersensitivity to hCG or any component of the formulation. Lupi-HCG 5000 Injection should be used with caution in patients with cardiovascular or thromboembolic disorders.