Gufitrig 5000IU Injection contains Human Chorionic Gonadotropin (hCG) at a concentration of 5000 International Units per dose. hCG is a glycoprotein hormone produced during pregnancy that mimics the action of luteinizing hormone (LH) by stimulating the gonads. This injection is primarily indicated for the treatment of infertility in both males and females. In males, Gufitrig is used to induce spermatogenesis and treat hypogonadism by stimulating testosterone production from Leydig cells in the testes. In females, it is employed to trigger ovulation and support the luteal phase in assisted reproductive technologies such as in vitro fertilization (IVF). Additionally, it may be used in prepubertal boys with cryptorchidism to facilitate testicular descent. The injection is administered intramuscularly or subcutaneously as per the prescribed dosing regimen. Contraindications include hypersensitivity to hCG or any component of the formulation, hormone-sensitive tumors, and certain reproductive cancers. Common adverse effects may include local injection site reactions, headache, irritability, and mild gynecomastia in males. Gufitrig should be used under strict medical supervision with appropriate monitoring of hormone levels and clinical response to optimize therapeutic outcomes and minimize risks.