Lixofate-O Oral Suspension Mint Sugar Free is a combination medication containing Sucralfate (1gm/10ml) and Oxetacaine (20mg/10ml), formulated to provide effective relief from gastrointestinal discomfort associated with ulcers and mucosal irritation. Sucralfate acts as a protective agent by forming a viscous, adhesive barrier over ulcer sites, thereby shielding the mucosa from gastric acid, pepsin, and bile salts, which facilitates healing. Oxetacaine, a local anesthetic, provides rapid symptomatic relief by numbing the mucosal lining, reducing pain and discomfort. The mint-flavored, sugar-free suspension enhances patient compliance, particularly for those requiring prolonged therapy or with sugar intake restrictions such as diabetics. Lixofate-O is indicated for the treatment of gastric and duodenal ulcers, gastritis, esophagitis, and other conditions involving mucosal damage or irritation. It is administered orally, with dosage and duration tailored according to clinical response and severity of the condition. The formulation’s dual action of mucosal protection and analgesia makes it suitable for both acute symptom control and mucosal healing. Caution is advised in patients with renal impairment, and concurrent use with antacids should be timed appropriately to avoid interference with Sucralfate’s efficacy. Overall, Lixofate-O Oral Suspension offers a well-tolerated and effective therapeutic option for managing upper gastrointestinal mucosal lesions.