Levogen M Tablet is a combination medication containing Levocetirizine 5 mg and Montelukast 10 mg, formulated for the management of allergic conditions such as allergic rhinitis and chronic urticaria. Levocetirizine, a third-generation non-sedative antihistamine, selectively inhibits peripheral H1 histamine receptors, thereby reducing symptoms like sneezing, nasal congestion, itching, and rhinorrhea. Montelukast, a leukotriene receptor antagonist, blocks leukotriene D4 at the cysteinyl leukotriene receptor in the lungs and bronchial tubes, preventing bronchoconstriction and inflammation commonly associated with asthma and allergic rhinitis. The synergistic action of these two agents provides comprehensive relief from both immediate and delayed allergic responses. Levogen M is indicated for patients requiring effective control of seasonal and perennial allergic rhinitis symptoms, as well as those with mild to moderate asthma or exercise-induced bronchoconstriction. The combination enhances patient compliance by reducing pill burden while maintaining efficacy. It is generally well tolerated; however, potential side effects may include headache, fatigue, dry mouth, or gastrointestinal disturbances. Use is contraindicated in patients with known hypersensitivity to either component. Caution is advised in patients with hepatic or renal impairment. Levogen M should be used under medical supervision with appropriate dosage adjustments as necessary.