Levobeta M 5mg/10mg Tablet is a combination medication containing Levocetirizine 5mg and Montelukast 10mg, indicated for the management of allergic conditions such as allergic rhinitis and chronic idiopathic urticaria. Levocetirizine, a third-generation non-sedating antihistamine, selectively inhibits peripheral H1 receptors, thereby reducing symptoms like sneezing, rhinorrhea, nasal itching, and urticaria. Montelukast, a leukotriene receptor antagonist, blocks leukotriene D4 at the cysteinyl leukotriene receptor, mitigating bronchoconstriction and inflammation associated with asthma and allergic rhinitis. The synergistic effect of these agents provides comprehensive relief from allergic symptoms by targeting multiple inflammatory pathways. Levobeta M is typically administered once daily, preferably in the evening, with or without food. It is generally well tolerated; however, potential side effects may include headache, fatigue, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with hepatic or renal impairment, and it should be used under medical supervision in pediatric and elderly populations. Levobeta M should not be used in patients with known hypersensitivity to its components. This combination therapy offers an effective option for patients inadequately controlled by monotherapy, improving quality of life through enhanced symptom control.