Kzole D 10mg/20mg Capsule is a combination medication containing Domperidone 10mg and Omeprazole 20mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by accelerating gastric emptying and improving esophageal sphincter tone, thereby reducing symptoms such as nausea, vomiting, and bloating. Omeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The synergistic action of these agents addresses both acid suppression and motility enhancement, providing comprehensive symptomatic relief. Kzole D is typically administered orally once daily before meals, with dosage and duration tailored to individual patient needs. It is contraindicated in patients with known hypersensitivity to either component and should be used cautiously in those with hepatic impairment or cardiac conditions due to potential side effects such as QT prolongation associated with Domperidone. Common adverse effects may include dry mouth, abdominal cramps, and headache. Consultation with a healthcare professional is essential prior to use to ensure appropriate therapy and monitoring.