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Kronostar 300 Tablet CR

Kronostar 300 Tablet CR

Valproic Acid (87mg) + Sodium Valproate (200mg)

Lupin Ltd
Epilepsy
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About This Medicine

Product description & overview

Kronostar 300 Tablet CR is a controlled-release formulation containing Sodium Valproate 200 mg and Valproic Acid 87 mg, indicated primarily for the management of epilepsy and bipolar disorder. The combination of these active ingredients acts as an anticonvulsant and mood stabilizer by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, thereby exerting an inhibitory effect on neuronal excitability. This dual mechanism helps in the prevention of various seizure types including absence seizures, complex partial seizures, and generalized tonic-clonic seizures. Additionally, Kronostar 300 Tablet CR is effective in stabilizing mood swings in patients with bipolar affective disorder, reducing the frequency and severity of manic episodes. The controlled-release formulation ensures a steady plasma concentration, minimizing peak-related side effects and enhancing patient compliance through once or twice-daily dosing. Common adverse effects may include gastrointestinal disturbances, tremors, weight gain, and sedation. Liver function tests and blood counts should be monitored regularly due to the risk of hepatotoxicity and hematological abnormalities. This medication should be used under strict medical supervision, with caution advised in pregnant women due to potential teratogenicity. Kronostar 300 Tablet CR offers a reliable therapeutic option for long-term management of seizure disorders and mood stabilization.

Active composition

Valproic Acid 87 mg

+1 more active ingredient

About Valproic Acid

Valproic Acid is an anticonvulsant medication primarily used to treat epilepsy and manic episodes associated with bipolar disorder. It is effective in controlling seizures by stabilizing electrical activity in the brain and is also utilized to prevent migraine headaches. Valproic Acid enhances the concentration of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve transmission, contributing to its calming effects. In summary, it helps manage seizures and mood disorders effectively.

How It Works

Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.

Medicine Strength
87 mg

All Active Ingredients

Valproic Acid87 mg
Sodium Valproate200 mg

Sodium Valproate

Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.

Safety Advice

Important precautions

Side Effect Occurrence

Based on clinical trials and patient reports.

Overall Tolerance

Most patients tolerate well

Only 2.3% reported effects

Common Side Effects

Headache8%
Nausea5%
Dizziness3%
Fatigue2%
Rash1%
Higher
Lower

Safety Advice

Alcohol

Kronostar 300 Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

High Risk

Pregnancy

Kronostar 300 Tablet CR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Medical Advice

Driving

Kronostar 300 Tablet CR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kronostar 300 Tablet CR may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.

Exercise Caution

Breastfeeding

Kronostar 300 Tablet CR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Consult Doctor

Kidney

Kronostar 300 Tablet CR should be used with caution in patients with liver disease. Dose adjustment of Kronostar 300 Tablet CR may be needed. Please consult your doctor. Use of Kronostar 300 Tablet CR is not recommended in patients with severe liver disease and active liver disease.

Regular Checkup

Customer Reviews

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