Ketomol-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Pantoprazole 40mg, indicated for the management of gastrointestinal disorders characterized by acid reflux, dyspepsia, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing the movement of the stomach and intestines, thereby alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. The synergistic action of these two agents in Ketomol-DSR Capsule offers comprehensive symptomatic relief by both improving gastric motility and reducing acid production. This combination is particularly beneficial in patients presenting with concurrent motility disorders and acid hypersecretion. Ketomol-DSR should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to either component, and caution in patients with underlying cardiac conditions due to Domperidone’s potential to prolong the QT interval. Adverse effects may include headache, dry mouth, abdominal cramps, and rare extrapyramidal symptoms. Regular monitoring and adherence to recommended dosages are advised to ensure optimal therapeutic outcomes.