Isonorm 60 SR Tablet contains Isosorbide Mononitrate 60 mg, a long-acting nitrate used primarily for the prevention and management of angina pectoris. Isosorbide Mononitrate acts as a vasodilator by relaxing vascular smooth muscle, leading to the dilation of peripheral veins and arteries. This results in reduced myocardial oxygen demand by decreasing preload and afterload, thereby alleviating chest pain associated with coronary artery disease. The sustained-release formulation ensures a gradual release of the active ingredient, providing prolonged therapeutic effects and maintaining stable plasma concentrations, which helps in minimizing the frequency of angina attacks. Isonorm 60 SR is indicated for prophylactic treatment rather than acute angina episodes. It is typically administered once or twice daily, depending on clinical judgment. Common side effects may include headache, dizziness, hypotension, and flushing, which are generally dose-related and tend to diminish with continued use. Caution is advised in patients with hypotension, severe anemia, or increased intracranial pressure. Concomitant use with phosphodiesterase inhibitors is contraindicated due to the risk of severe hypotension. Regular monitoring and adherence to prescribed dosage are essential to optimize therapeutic outcomes and minimize adverse effects.