Increglip M 50mg/500mg Tablet PR

Increglip M 50mg/500mg Tablet PR
Sitagliptin (50mg) + Metformin (500mg)
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About This Medicine
Product description & overview
Increglip M 50mg/500mg Tablet PR is a combination oral antidiabetic medication containing Sitagliptin 50mg and Metformin 500mg, indicated for the management of type 2 diabetes mellitus. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the incretin system by increasing levels of active incretin hormones, which regulate glucose homeostasis by increasing insulin synthesis and release from pancreatic beta cells and decreasing glucagon secretion from alpha cells, thereby reducing hepatic glucose production. Metformin, a biguanide, primarily acts by decreasing hepatic gluconeogenesis and improving peripheral insulin sensitivity, leading to enhanced glucose uptake and utilization. The combination provides complementary mechanisms to achieve better glycemic control in patients inadequately controlled by diet, exercise, and monotherapy. Increglip M is administered orally, with a recommended dosage tailored to individual patient needs and glycemic response. It is generally well tolerated; however, common adverse effects may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort, primarily attributed to metformin. Caution is advised in patients with renal impairment, hepatic dysfunction, or conditions predisposing to lactic acidosis. Regular monitoring of blood glucose levels and renal function is recommended during therapy to optimize efficacy and safety.
Active composition
Sitagliptin 50 mg
+1 more active ingredient
About Sitagliptin
Sitagliptin is an oral antidiabetic medication used to manage type 2 diabetes. It works by increasing insulin secretion and decreasing glucagon levels. Sitagliptin may cause side effects such as upper respiratory infections. In summary, Sitagliptin is effective for controlling blood sugar.
How It Works
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
All Active Ingredients
Metformin
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Pregnancy
Information regarding the use of Increglip M 50mg/500mg Tablet PR during pregnancy is not available. Please consult your doctor.
Medical Advice
Driving
Increglip M 50mg/500mg Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Increglip M 50mg/500mg Tablet PR may be needed. Please consult your doctor. Use of Increglip M 50mg/500mg Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
Breastfeeding
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Increglip M 50mg/500mg Tablet PR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Customer Reviews
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