Imdur 60mg Tablet PR contains Isosorbide Mononitrate, a long-acting nitrate used primarily for the prevention and management of angina pectoris due to coronary artery disease. This medication functions as a vasodilator by relaxing vascular smooth muscle, leading to the dilation of peripheral veins and arteries, which reduces myocardial oxygen demand by decreasing preload and afterload. Imdur 60mg is formulated as a prolonged-release tablet, ensuring a sustained therapeutic effect and improved patient compliance through once-daily dosing. It is indicated for the prophylactic treatment of chronic stable angina, helping to reduce the frequency and severity of anginal attacks. The onset of action occurs within 30 to 60 minutes, with effects lasting up to 24 hours. Caution is advised in patients with hypotension, severe anemia, or increased intracranial pressure. Common adverse effects may include headache, dizziness, flushing, and hypotension. Imdur should not be used concomitantly with phosphodiesterase inhibitors due to the risk of severe hypotension. Dosage adjustments may be necessary in renal or hepatic impairment. Patients should be advised to adhere strictly to prescribed dosing schedules to maintain effective plasma concentrations and avoid nitrate tolerance.