Hedfree Tablet contains a combination of Sumatriptan 85 mg and Naproxen 500 mg, formulated for the acute treatment of migraine attacks with or without aura in adults. Sumatriptan, a selective serotonin 5-HT1 receptor agonist, acts by constricting intracranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides, thereby alleviating migraine pain and associated symptoms such as nausea and photophobia. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), provides additional analgesic and anti-inflammatory effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis responsible for pain and inflammation. The combination therapy offers synergistic benefits, improving efficacy in migraine relief compared to monotherapy with either agent. Hedfree Tablet is indicated for patients who require rapid and effective migraine symptom control. It is contraindicated in individuals with known hypersensitivity to sumatriptan, naproxen, other NSAIDs, or aspirin, as well as those with cardiovascular disease, uncontrolled hypertension, or a history of stroke. Caution is advised in patients with hepatic or renal impairment. Common adverse effects may include dizziness, nausea, dry mouth, and gastrointestinal discomfort. Patients should adhere to prescribed dosages and consult healthcare professionals for appropriate use and potential drug interactions.