Goodprazole D 10/20 Tablet is a combination pharmaceutical formulation containing Domperidone 10 mg and Pantoprazole 20 mg, designed for the effective management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating associated with delayed gastric emptying and gastroparesis. Pantoprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing symptomatic relief in conditions like gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcer disease. The synergistic action of these two agents addresses both acid-related mucosal damage and motility disturbances, enhancing therapeutic outcomes. Goodprazole D is indicated for the treatment of acid-related gastrointestinal disorders accompanied by motility dysfunction. It should be administered as per physician’s guidance, with dosage adjustments based on clinical response and patient tolerance. Caution is advised in patients with known hypersensitivity to either component, and it is contraindicated in individuals with gastrointestinal hemorrhage, obstruction, or perforation. Monitoring for potential side effects such as headache, dry mouth, or abdominal discomfort is recommended during therapy.