Glycinorm Total 60 Tablet SR

Glycinorm Total 60 Tablet SR
Gliclazide (60mg) + Pioglitazone (15mg) + Metformin (500mg)
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About This Medicine
Product description & overview
Glycinorm Total 60 Tablet SR is a combination oral antidiabetic medication containing Gliclazide 60 mg, Pioglitazone 15 mg, and Metformin 500 mg, formulated for sustained release to optimize glycemic control in patients with type 2 diabetes mellitus. Gliclazide, a sulfonylurea, stimulates pancreatic beta-cell insulin secretion, thereby reducing blood glucose levels. Pioglitazone, a thiazolidinedione, enhances peripheral insulin sensitivity by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), improving glucose uptake in adipose tissue and muscle. Metformin, a biguanide, decreases hepatic gluconeogenesis and enhances peripheral glucose utilization, contributing to improved insulin sensitivity. The combination targets multiple pathophysiological defects of type 2 diabetes, providing complementary mechanisms to achieve better glycemic control. Glycinorm Total 60 Tablet SR is indicated for patients inadequately controlled on monotherapy or dual therapy with these agents. It is essential to monitor blood glucose levels regularly and adjust dosage based on therapeutic response and tolerability. Caution is advised in patients with renal or hepatic impairment, heart failure, or risk factors for lactic acidosis. Adverse effects may include hypoglycemia, gastrointestinal disturbances, weight gain, and edema. This combination therapy should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring.
Active composition
Pioglitazone 15 mg
+2 more active ingredients
About Pioglitazone
Pioglitazone is an antidiabetic medication used to treat type 2 diabetes. It works by improving insulin sensitivity and regulating blood sugar levels. Pioglitazone is effective in managing diabetes. In summary, Pioglitazone is beneficial for treating type 2 diabetes.
How It Works
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.
All Active Ingredients
Gliclazide
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Metformin
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Glycinorm Total 60 Tablet SR.
High Risk
Pregnancy
Glycinorm Total 60 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Glycinorm Total 60 Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Liver
Glycinorm Total 60 Tablet SR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Breastfeeding
Glycinorm Total 60 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Glycinorm Total 60 Tablet SR is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Regular Checkup
Customer Reviews
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