Glopan-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Pantoprazole 40 mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing gastric emptying and increasing lower esophageal sphincter tone, thereby reducing symptoms of nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The synergistic action of these agents provides effective symptomatic relief and addresses both motility and acid secretion abnormalities. Glopan-DSR is typically prescribed for patients presenting with GERD symptoms such as heartburn, acid regurgitation, and epigastric discomfort, as well as for those with delayed gastric emptying. The capsule should be administered as directed by a healthcare professional, usually before meals. Caution is advised in patients with known hypersensitivity to either component, underlying cardiac conditions, or hepatic impairment. Adverse effects may include headache, dry mouth, abdominal cramps, or rare extrapyramidal symptoms. Regular monitoring and adherence to prescribed dosage enhance therapeutic outcomes and minimize risks.