Glimfirst-MP 2 Tablet SR

Glimfirst-MP 2 Tablet SR
Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg)
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About This Medicine
Product description & overview
Glimfirst-MP 2 Tablet SR is a combination oral antidiabetic medication containing Glimepiride (2mg), Metformin (500mg), and Pioglitazone (15mg), formulated to improve glycemic control in patients with type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta cells to enhance insulin secretion. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity. Pioglitazone, a thiazolidinedione, enhances insulin sensitivity in adipose tissue, muscle, and the liver by activating peroxisome proliferator-activated receptor gamma (PPAR-γ). The sustained-release formulation ensures a gradual release of active ingredients, promoting better patient compliance and minimizing gastrointestinal side effects commonly associated with Metformin. Glimfirst-MP 2 is indicated for patients inadequately controlled on diet, exercise, and monotherapy or dual therapy with any of its components. It should be used with caution in patients with hepatic or renal impairment, heart failure, or a history of bladder cancer due to the risk profile of Pioglitazone. Regular monitoring of blood glucose levels, liver function tests, and renal parameters is recommended during therapy. This combination therapy offers a comprehensive approach to managing hyperglycemia by targeting multiple pathophysiological defects in type 2 diabetes.
Active composition
Metformin 500 mg
+2 more active ingredients
About Metformin
Metformin is an oral antihyperglycemic agent used to manage type 2 diabetes mellitus. It works by decreasing glucose production in the liver and improving insulin sensitivity. Metformin is effective in controlling blood sugar levels and preventing diabetes-related complications. In summary, Metformin is vital for managing type 2 diabetes.
How It Works
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
All Active Ingredients
Glimepiride
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Pioglitazone
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Glimfirst-MP 2 Tablet SR.
High Risk
Pregnancy
Glimfirst-MP 2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Glimfirst-MP 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Glimfirst-MP 2 Tablet SR may be needed. Please consult your doctor. Use of Glimfirst-MP 2 Tablet SR is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Glimfirst-MP 2 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Glimfirst-MP 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Glimfirst-MP 2 Tablet SR may be needed. Please consult your doctor. Use of Glimfirst-MP 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
Customer Reviews
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