Glamzole-D Capsule PR is a combination pharmaceutical formulation containing Domperidone 30 mg and Pantoprazole 40 mg, designed for the management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and gastric discomfort associated with delayed gastric emptying and gastroparesis. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related disorders including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The combination offers synergistic benefits by simultaneously addressing gastric motility and acid secretion abnormalities. Glamzole-D Capsule PR is indicated for patients presenting with upper gastrointestinal symptoms where both acid suppression and prokinetic effects are desired. It is administered orally, preferably before meals, and should be used under medical supervision, especially in patients with hepatic impairment or cardiac conditions due to potential side effects such as QT prolongation associated with Domperidone. Contraindications include hypersensitivity to either component and concurrent use with medications known to prolong the QT interval. This combination therapy enhances patient compliance by reducing pill burden while providing comprehensive symptom control in functional dyspepsia and related disorders.