Gevel Trio 1 Tablet ER
Gevel Trio 1 Tablet ER
Glimepiride (1mg) + Metformin (500mg) + Voglibose (0.3mg)
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About This Medicine
Product description & overview
Gevel Trio 1 Tablet ER is a combination oral antidiabetic medication containing Glimepiride 1mg, Metformin 500mg, and Voglibose 0.3mg, formulated for extended-release administration. This fixed-dose combination is indicated for the management of type 2 diabetes mellitus, particularly in patients inadequately controlled by diet, exercise, and monotherapy. Glimepiride, a sulfonylurea, stimulates pancreatic beta-cell insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, improves insulin sensitivity by decreasing hepatic glucose production and enhancing peripheral glucose uptake. Voglibose, an alpha-glucosidase inhibitor, delays carbohydrate absorption from the gastrointestinal tract, minimizing postprandial hyperglycemia. The extended-release formulation allows for sustained plasma drug levels, potentially improving glycemic control and patient compliance by reducing dosing frequency. Gevel Trio 1 Tablet ER should be used as part of a comprehensive diabetes management plan including diet and exercise. Caution is advised in patients with renal or hepatic impairment, and regular monitoring of blood glucose and renal function is recommended. Potential adverse effects include hypoglycemia, gastrointestinal disturbances, and lactic acidosis. This combination therapy offers a multifaceted approach to glycemic control by targeting different pathophysiological mechanisms of type 2 diabetes.
Active composition
Glimepiride 1 mg
+2 more active ingredients
About Glimepiride
Glimepiride is an oral hypoglycemic agent used to manage blood sugar levels in patients with type 2 diabetes mellitus. It works by stimulating the pancreas to release more insulin, thereby lowering blood glucose levels and preventing the symptoms associated with diabetes. Glimepiride is often prescribed alongside diet and exercise to enhance glycemic control and reduce the risk of diabetes-related complications, such as kidney damage and neuropathy. In summary, Glimepiride is an essential medication for controlling blood sugar levels in type 2 diabetes patients.
How It Works
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
All Active Ingredients
Metformin
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Voglibose
Voglibose inhibits intestinal alpha-glucosidases, delaying carbohydrate digestion and absorption, thus lowering postprandial glucose levels.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Gevel Trio 1 Tablet ER.
High Risk
Pregnancy
Gevel Trio 1 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Gevel Trio 1 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Gevel Trio 1 Tablet ER may be needed. Please consult your doctor. Gevel Trio 1 Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Gevel Trio 1 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Gevel Trio 1 Tablet ER is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. Use of Gevel Trio 1 Tablet ER is, however, not recommended in patients with severe kidney disease.
Regular Checkup
Customer Reviews
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