Eprisan D SR Capsule is a combination medication containing Eperisone 150 mg and Diclofenac 100 mg, formulated for the management of musculoskeletal conditions characterized by muscle spasm and inflammation. Eperisone acts as a centrally acting muscle relaxant, reducing muscle tone by inhibiting spinal reflexes, thereby alleviating muscle stiffness and improving mobility. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), provides potent analgesic and anti-inflammatory effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins responsible for pain and inflammation. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing efficacy and patient compliance by reducing dosing frequency. Eprisan D SR Capsule is indicated for the treatment of conditions such as acute and chronic musculoskeletal pain, spasticity associated with neurological disorders, and inflammatory joint diseases. It should be used under medical supervision, considering contraindications such as hypersensitivity to NSAIDs, active gastrointestinal ulcers, or severe hepatic or renal impairment. Common adverse effects may include gastrointestinal discomfort, dizziness, or allergic reactions. Caution is advised in patients with cardiovascular risk factors. Overall, Eprisan D SR Capsule offers a synergistic approach to pain relief and muscle relaxation, improving functional outcomes in patients with musculoskeletal disorders.