Liobec ER 20 Tablet contains Baclofen 20mg, a centrally acting skeletal muscle relaxant indicated for the management of spasticity resulting from conditions such as multiple sclerosis, spinal cord injuries, or other neurological disorders. Baclofen exerts its therapeutic effect by stimulating GABA-B receptors in the central nervous system, leading to inhibition of monosynaptic and polysynaptic reflexes at the spinal level, thereby reducing muscle spasticity and associated pain. The extended-release formulation of Liobec ER 20 allows for a sustained and controlled release of baclofen, providing consistent plasma concentrations and improved patient compliance through once or twice daily dosing. It is essential to initiate treatment at a low dose and gradually titrate to the effective dose to minimize adverse effects, which may include drowsiness, dizziness, weakness, and gastrointestinal disturbances. Abrupt discontinuation should be avoided due to the risk of withdrawal symptoms such as hallucinations, seizures, or rebound spasticity. Liobec ER 20 should be used with caution in patients with renal impairment, epilepsy, or a history of psychiatric disorders. Concomitant use with CNS depressants may potentiate sedative effects. This medication should be prescribed and monitored by healthcare professionals experienced in managing spasticity to optimize therapeutic outcomes and minimize risks.