Zytor-Plus 10 Tablet is a combination medication containing Spironolactone 50 mg and Torasemide 10 mg, indicated for the management of edema associated with congestive heart failure, liver cirrhosis, and nephrotic syndrome, as well as for the treatment of hypertension. Spironolactone is a potassium-sparing diuretic and aldosterone antagonist that promotes sodium and water excretion while conserving potassium, thereby reducing fluid overload and preventing hypokalemia. Torasemide is a loop diuretic that inhibits sodium and chloride reabsorption in the thick ascending limb of the loop of Henle, resulting in potent diuresis and natriuresis. The synergistic action of these agents provides effective fluid removal with a balanced electrolyte profile, minimizing the risk of potassium imbalance commonly seen with loop diuretics alone. Zytor-Plus 10 is particularly useful in patients requiring enhanced diuretic efficacy without significant potassium loss. It should be used under medical supervision with regular monitoring of electrolytes, renal function, and blood pressure to avoid adverse effects such as hyperkalemia, dehydration, hypotension, or renal impairment. Contraindications include anuria, acute renal insufficiency, hyperkalemia, and hypersensitivity to either component. This combination therapy offers a convenient and effective approach to managing fluid retention and hypertension in various clinical settings.