Zoro-NT 400 Tablet is a combination pharmaceutical formulation containing Gabapentin 400 mg and Nortriptyline 10 mg, indicated primarily for the management of neuropathic pain and certain types of chronic pain syndromes. Gabapentin, an anticonvulsant, modulates calcium channels in the nervous system, thereby reducing neuronal excitability and alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, exerts analgesic effects by inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. The synergistic action of these agents provides enhanced pain relief compared to monotherapy, making Zoro-NT 400 effective in conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. This combination may also be beneficial in managing comorbid depressive symptoms often associated with chronic pain. Zoro-NT 400 should be administered under medical supervision, with dosage adjustments based on therapeutic response and tolerability. Common adverse effects include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disease, or a history of seizures. Concomitant use with other central nervous system depressants requires careful monitoring. Pregnant and lactating women should use this medication only if clearly needed. Regular follow-up is recommended to assess efficacy and safety during treatment.