Zml Nasal Spray/Drop contains Xylometazoline 0.1% w/v, a topical nasal decongestant indicated for the relief of nasal congestion associated with conditions such as allergic rhinitis, sinusitis, and the common cold. Xylometazoline acts as an alpha-adrenergic receptor agonist, producing vasoconstriction of the nasal mucosal blood vessels, thereby reducing swelling and congestion. This mechanism facilitates improved nasal airflow and eases breathing. Zml Nasal Spray/Drop is intended for short-term use, typically not exceeding 3 to 5 consecutive days, to prevent rebound congestion or rhinitis medicamentosa. It is administered intranasally, with dosage adjusted according to age and severity of symptoms. Caution is advised in patients with hypertension, cardiovascular disease, hyperthyroidism, diabetes, or prostatic hypertrophy, as systemic absorption may exacerbate these conditions. Use during pregnancy and lactation should be under medical supervision. Common adverse effects include nasal irritation, dryness, and sneezing. Overuse may lead to nasal mucosal damage and dependency. Patients should avoid concurrent use with other sympathomimetic agents or monoamine oxidase inhibitors. Zml Nasal Spray/Drop provides rapid onset of action, typically within minutes, offering effective symptomatic relief of nasal congestion to enhance patient comfort and respiratory function.