Zix-R OD Capsule SR

Zix-R OD Capsule SR
Aceclofenac (200mg) + Rabeprazole (20mg)
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About This Medicine
Product description & overview
Zix-R OD Capsule SR is a combination pharmaceutical formulation containing Aceclofenac 200 mg and Rabeprazole 20 mg, designed for the management of inflammatory and acid-related gastrointestinal conditions. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts potent analgesic and anti-inflammatory effects by selectively inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis responsible for pain and inflammation. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, promoting mucosal healing and preventing NSAID-induced gastropathy. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, enhancing patient compliance through once-daily dosing. Zix-R OD Capsule SR is indicated for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other musculoskeletal disorders requiring anti-inflammatory therapy, particularly in patients at risk of developing NSAID-associated gastric ulcers or dyspepsia. Caution is advised in patients with hypersensitivity to NSAIDs or PPIs, hepatic or renal impairment, and cardiovascular disease. Common adverse effects may include gastrointestinal discomfort, headache, dizziness, and rare hypersensitivity reactions. This combination should be used under medical supervision with periodic monitoring to optimize therapeutic outcomes and minimize potential risks.
Active composition
Aceclofenac 200 mg
+1 more active ingredient
About Aceclofenac
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) used to alleviate pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by blocking the COX enzymes responsible for producing prostaglandins, which mediate pain and inflammation. Aceclofenac is effective in reducing symptoms and improving joint function. In summary, Aceclofenac is beneficial in managing pain and inflammation in various arthritic conditions.
How It Works
Aceclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which are responsible for pain and inflammation.
All Active Ingredients
Rabeprazole
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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