Zitran 200 Capsule contains Itraconazole 200 mg, a broad-spectrum triazole antifungal agent used for the treatment of various systemic and superficial fungal infections. Itraconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting cell membrane integrity and leading to fungal cell death. This medication is indicated for the treatment of infections such as aspergillosis, blastomycosis, histoplasmosis, onychomycosis, and candidiasis, including oropharyngeal and esophageal candidiasis. Zitran 200 Capsule is particularly effective against dermatophytes, yeasts, and molds. It is administered orally and exhibits good bioavailability, with enhanced absorption when taken with food. The dosage and duration of therapy depend on the type and severity of the infection, and treatment should be guided by clinical response and laboratory findings. Common adverse effects may include gastrointestinal disturbances, headache, dizziness, and elevated liver enzymes; therefore, liver function monitoring is recommended during prolonged therapy. Caution is advised in patients with hepatic impairment and those receiving concomitant medications metabolized by cytochrome P450 enzymes due to potential drug interactions. Zitran 200 Capsule should be used under medical supervision to ensure safe and effective antifungal therapy.