Zisper Plus Tablet contains a combination of Risperidone (3 mg) and Trihexyphenidyl (2 mg), formulated for the management of psychiatric disorders. Risperidone is an atypical antipsychotic agent that exerts its therapeutic effects primarily through antagonism of dopamine D2 and serotonin 5-HT2A receptors, thereby helping to restore the chemical balance in the brain and alleviate symptoms of schizophrenia, bipolar disorder, and irritability associated with autism. Trihexyphenidyl is an anticholinergic agent used to counteract extrapyramidal side effects such as tremors, rigidity, and bradykinesia, which may arise during antipsychotic treatment. The combination in Zisper Plus Tablet offers both antipsychotic efficacy and mitigation of movement disorders, improving patient compliance and overall treatment outcomes. It is indicated for patients requiring antipsychotic therapy who are prone to or experiencing extrapyramidal symptoms. Dosage and administration should be individualized based on clinical response and tolerability, with careful monitoring for adverse effects including sedation, orthostatic hypotension, dry mouth, and potential metabolic changes. Use is contraindicated in patients with hypersensitivity to either component, severe central nervous system depression, or narrow-angle glaucoma. Zisper Plus should be prescribed and used under strict medical supervision to ensure safety and effectiveness.