Zisper Forte Tablet contains a combination of Risperidone (4 mg) and Trihexyphenidyl (2 mg), formulated to manage symptoms associated with schizophrenia, bipolar disorder, and extrapyramidal side effects induced by antipsychotic treatment. Risperidone is an atypical antipsychotic that acts by antagonizing dopamine D2 and serotonin 5-HT2A receptors, thereby helping to restore the chemical balance in the brain and reduce symptoms such as hallucinations, delusions, and mood swings. Trihexyphenidyl is an anticholinergic agent used to alleviate extrapyramidal symptoms, including tremors, rigidity, and bradykinesia, which may arise as adverse effects during antipsychotic therapy. The combination in Zisper Forte offers a dual approach by addressing both psychotic symptoms and movement disorders, enhancing patient compliance and therapeutic outcomes. It is indicated for the treatment of schizophrenia, acute manic or mixed episodes associated with bipolar disorder, and prevention or management of extrapyramidal symptoms. Dosage and administration should be individualized based on clinical response and tolerability, under strict medical supervision. Caution is advised in patients with cardiovascular, hepatic, or renal impairment. Common side effects include sedation, dizziness, dry mouth, and gastrointestinal disturbances. Regular monitoring is recommended to optimize efficacy and minimize adverse effects.